Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.164.2-164.2
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- 2003
In vitro neural differentiation of human embryonic stem cells
- Park, Jae-Hyun (Antibody Engineering Research unit, Korea Research Institute of Biosience and biotechnology) ;
- Shin, Hwa-Yean (MizMedi Medical Research Center) ;
- Kang, Yun-Hee (Department of Pharmacy, College of Pharmacy, Chung-nam National University) ;
- Kang, Young-Kook (Department of Pharmacy, College of Pharmacy, Chung-nam National University) ;
- Lee, Jung-Bok (Department of Pharmacy, College of Pharmacy, Chung-nam National University) ;
- Yoon, Hyun-Soo (Department of Pharmacy, College of Pharmacy, Chung-nam National University) ;
- Ryu, Chun-Jeih (Department of Pharmacy, College of Pharmacy, Chung-nam National University) ;
- Myung, Pyung-Keun (Department of Pharmacy, College of Pharmacy, Chung-nam National University) ;
- Hong, Hyo-Jeong (Department of Pharmacy, College of Pharmacy, Chung-nam National University)
- Published : 2003.10.01
Abstract
Human embryonic stem (ES) cell lines derived from the inner cell mass of human blastocysts have potential to differentiate into any cell types. We have established in vitro neural differentiation of human ES cells. After the formation of embroid bodies (EBs), the differentiating EBs formed neural tube-like rosettes in the presence of basic fibroblast growth factor (bFGF). The rosettes were selectively isolated by the treatment of dispase and cultured in a medium for human neural precursors in the presence of bFGF. (omitted)
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