Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.123.3-124
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- 2003
Whitening Activity of Phenylpropanoid Compounds
- Yoon, Mi-Yun (College of Pharmacy, Chung-Ang University) ;
- Park, Young-Mi (College of Pharmacy, Chung-Ang University) ;
- Lee, Jin-Hee (College of Pharmacy, Chung-Ang University) ;
- Kim, Youn-Joung (College of Pharmacy, Chung-Ang University) ;
- Kim, Chang-Jong (College of Pharmacy, Chung-Ang University) ;
- Sim, Sang-Soo (College of Pharmacy, Chung-Ang University)
- Published : 2003.10.01
Abstract
To investigate the relationship between structure and biological activity of phenylpropanoids, we measured effects of phenylpropanoids on anti-oxidant and whitening activity. In DPPH radical scavenging activity, caffeic acid analogues had anti-oxidant activity in a dose-dependent manner. Although phenylpropanoids did not inhibit purified tyrosinase activity, they significantly inhibited tyrosinase activity and melanin production in MSH-stimulated B16 melanoma cells. (omitted)
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