Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Induction of cyclooxygenase-2 by collagen and gelatin in murine macrophages

  • Kim, Ji-Young (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University) ;
  • Moon, Ae-Ran (Division of Food Science, Jinju International University) ;
  • Kim, Hyung-Gyun (Division of Food Science, Jinju International University) ;
  • Choi, Chul-Yung (Division of Food Science, Jinju International University) ;
  • Chung, Yung-Chul (Division of Food Science, Jinju International University) ;
  • You, Ho-Jin (Division of Food Science, Jinju International University) ;
  • Jeong, Hye-Gwang (Division of Food Science, Jinju International University)
  • Published : 2003.10.01
Download PDF
⟨ Previous Next ⟩

Abstract

Gelatin protein is derived from animal collagen tissues and is therefore present in many kinds of animal protein food. The biological origin and biocompatibility of gelatin has led to wide-ranging applications in the pharmaceutical and medical fields; for example, as sealants for vascular prostheses, bone-repairing materials, wound healing agents and scaffolds for tissue engineering purposes. In the present study, we investigated the effects of collagen and gleatin on the cyclooxygenase-2 (COX-2) gene which plays a crucial role in many physiological and pathological processes in macrophages. (omitted)

Keywords