Antioxidative Effect of Houttuynia cordata Thunb in TCDD-Damaged Rats

  • Kim, Hee-Jin (Department of Bioscience & Biotechnology, Silla University) ;
  • Lee, Sang-Hun (Department of Bioscience & Biotechnology, Silla University) ;
  • Lee, Jin-Young (Department of Bioscience & Biotechnology, Silla University) ;
  • Ha, Bae-Jin (Department of Bioscience & Biotechnology, Silla University)
  • Published : 2003.10.01

Abstract

Houttuynia cordata Thunb (HCT) is a herbal plant growing in China, Japan and Korea. According to the records of the Chinese medicine, this plant has been used as folk medicine for analgesics, beriberi, edema, hepatitis, icterus, etc. TCDD (2, 3, 7, 8 -tetrachlorodibenzo-p-dioxin), one of the notorious toxic environmental pollutants, damages various organs including liver and is regarded as an endocrine disrupter. After 7 days from TCDD (1$\mu$g/kg) injection, HCT (200 mg/kg) was administered into rats intraperitoneally for 4 weeks. (omitted)

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