Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

A study on the evaluation of artificial cartilage using synthetic biodegradable polymers

  • Oh, Ho-Jung (Korea Food and Drug Administration, Biologics Evaluation Department, Blood Products Division) ;
  • Lee, Nam-Kyung (Korea Food and Drug Administration, Biologics Evaluation Department, Blood Products Divisio) ;
  • Kim, Soon-Nam (Korea Food and Drug Administration, Biologics Evaluation Department, Blood Products Divisio) ;
  • Hong, Choong-Man (Korea Food and Drug Administration, Biologics Evaluation Department, Blood Products Divisio) ;
  • Lee, Ki-Hong (Korea Food and Drug Administration, Biologics Evaluation Department, Blood Products Divisio) ;
  • Yoo, Si-Hyung (Korea Food and Drug Administration, Biologics Evaluation Department, Blood Products Divisio) ;
  • Shin, In-Soo (Korea Food and Drug Administration, Biologics Evaluation Department, Blood Products Divisio) ;
  • Lim, Jae-Hyun (Korea Food and Drug Administration, Biologics Evaluation Department, Blood Products Divisio) ;
  • Choi, Seung-Eun (Korea Food and Drug Administration, Biologics Evaluation Department, Blood Products Division)
  • Published : 2003.10.01
Download PDF
⟨ Previous Next ⟩

Abstract

Tissue engineering has arisen to address the extreme shortage of tissues and organs for transplantation and repair. One of the most successful techniques has been the seeding and culturing cells on three-dimensional biodegradable scaffolds in vitro followed by implantaion in vivo. We used PLA and PLGA as biodegradable polymers and rabbit chondrocytes were isolated and applied to PLA and PLGA to make artificial cartilage. To evaluate the biocompatibility and biological safety of polymers, in vitro cytotoxicity and in vivo animal tests were investigated. (omitted)

Keywords