Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.95.1-95.1
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- 2003
Anti-apoptotic effect of water extract of rheum undulatum in pancreatic $\beta$ -Cell, HIT-T15
- Yoon, Seo-Hyun (College of Pharmacy, Kyung Hee University) ;
- Hong, Mee-Suk (College of Medicine, Kyung Heel University) ;
- Chung, Joo-Ho (College of Medicine, Kyung Heel University) ;
- Chung, Sung-Hyun (College of Medicine, Kyung Heel University)
- Published : 2003.10.01
Abstract
Sopungsungi-won has been used as a traditional medicine for diabetes and it has been proved evidently as a potential remedy for type 2 diabetes mellitus. Both in vivo and in vitro experiments with water extract of Sopungsungi-won have been reported to exhibit anti-diabetic effects in our previous studies. In the present study, we have chosen Rheum undulatum (RU), which is the main component of Sopungsungi-won, to examine its anti-apoptotic effect on pancreatic b-cells, HIT-T15, against oxidative stress induced by hydrogen peroxide (H
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