Effects of Dioscorea daemona Roxb. (stem) extract on the inflammatory responses and antioxidant system

  • Park, Eun-Mi (Department of Food and Nutrition, Kyunghee University) ;
  • Hwang, Jae-Kwan (Department of Biotechnology & Bioproducts Research Center, Yonsei University) ;
  • Koo, Sung-Ja (Department of Food and Nutrition, Kyunghee University)
  • Published : 2003.10.01

Abstract

This study was undertaken in order to investigate the effects of Dioscorea daemona stem on the inflammatory reactions and antioxidant system in vivo. The methanolic extract of Dioscorea daemona stem, administered by gavage at the dose of 0.2 $\mu\textrm{g}$/kg, showed anti-inflammatory and anti-allergic (typeIV) effects in different test models. We also showed that plasma antioxidant enzyme activities, lipid peroxidation and HDL cholesterol levels are affected by administration (0.2 $\mu\textrm{g}$/kg body weight, for 3 weeks) of Dioscorea daemona stem extract in rats. (omitted)

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