Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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DETERMINATION OF SIMVASTATIN IN HUMAN PLASMA BY COLUMN SWITCHING HPLC WITH UV DETECTION

  • Ban, Eun-Mi (Physical Pharmacy Laboratory, College of Pharmacy, Seoul National University) ;
  • Kim, Bae-Chan (Physical Pharmacy Laboratory, College of Pharmacy, Seoul National University) ;
  • Park, Tae-Hwan (Physical Pharmacy Laboratory, College of Pharmacy, Seoul National University) ;
  • Kim, Chong-Kook (Physical Pharmacy Laboratory, College of Pharmacy, Seoul National University)
  • Published : 2003.04.01
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Abstract

Purpose. The purpose of this study was to develop and validate sensitive and specific analytical method for determinination of simvastatin in human plasma by the column-switching high-performance liquid chromatography (HPLC) system with UV detection. Methods. Simvastatin and internal standard were extracted into diethyl ether from plasma. (omitted)

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