LDL-Antioxidant activity of 6-hydroxyeugenol from Spiraea blumei

  • Lee, Dae-Woo (Korea Research Institute of Bioscience and Biotechnology) ;
  • Kim, Ju-Ryoung (Korea Research Institute of Bioscience and Biotechnolog) ;
  • Lee, Woo-Song (Korea Research Institute of Bioscience and Biotechnolog) ;
  • Cho, Kyung-Hyun (Korea Research Institute of Bioscience and Biotechnolog) ;
  • Bae, Ki-Hwan (College of Pharmacy, Chungnam National University) ;
  • Jeoung, Tae-Sook (Korea Research Institute of Bioscience and Biotechnology)
  • Published : 2003.04.01

Abstract

Low density lipoprotein (LOL) is the major cholesterol carrier in the blood stream. Also, LDL oxidation has been proposed as an important step in the formation of atherosclerotic lesion. Thus, protection of LDL from oxidation is needed to prevent or to retard the progression of atherosclerosis. In this study, 6-hydroxyeugenol was isolated from the methanolic extract of the Spiraea blumei and the sructure was elucidated by spectroscopic data analysis. (omitted)

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