Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.249.2-250
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- 2003
3-D QSAR Studies on Thiazole and Triazole Antifungal Agents by CoMFA and CoMSIA
- Thai, Khac-Minh (College of Pharmacy, Sungkyunkwan University) ;
- Tran, Thanh-Dao (College of Pharmacy, Kangwon National University) ;
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Park, Hyun-Ju
(College of Pharmacy, Sungkyunkwan University)
- Published : 2003.04.01
Abstract
3D-QSAR analyses by CoMFA and CoMSIA were conducted on a series of thiazole and triazole analogues with respect to their antifungal activities against Microsporum gypseum. A total of twenty analogues were used for the derivation of the 3D-QSAR models (training set). Thesuperposition of the compounds was performed by applying the FlexS with shape-based screening method. (omitted)
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