The Role of Korea Chemical Bank in "Hit to Lead" process of Drug Discovery

  • Kim, Sun-Woo (Korea Research Institute of Chemical Technology) ;
  • Kim, Dong-Wook (Korea Research Institute of Chemical Technolog) ;
  • Kim, Sun-Ho (Korea Research Institute of Chemical Technolog) ;
  • Choi, Yeon-Joo (Korea Research Institute of Chemical Technolog) ;
  • Kim, Joo-Young (Korea Research Institute of Chemical Technolog) ;
  • Han, Mi-Jung (Korea Research Institute of Chemical Technolog) ;
  • Kim, Oke-Kil (Korea Research Institute of Chemical Technolog) ;
  • Kil, Kyong-Ok (Korea Research Institute of Chemical Technolog) ;
  • Kim, Sung-Soo (Korea Research Institute of Chemical Technology)
  • Published : 2003.04.01

Abstract

The Korea Chemical Bank (KCB) has more than 80,000 compound collections. provided from many companies, academies and institutes. KCB has supported high-throughput screening (HTS) against 80 biological targets and identified a number of hits over 20 targets. These hits were first validated by confirming the purity and novelty of anticipated compound. We also determined their physiochemical properties. (omitted)

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