Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Cytotoxic activity of (2S, 3R, 4E) 5-Aryl-4-pentene-1,3-diol-2-aminoueras

  • Im, C.U. (College of Pharmacy, Chung-ang University) ;
  • Kim, Y.H. (College of Pharmacy, Chung-ang University) ;
  • Jyung, M.L. (College of Pharmacy, Chung-ang University) ;
  • Lim, C.B. (College of Pharmacy, Chung-ang University)
  • Published : 2003.04.01
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Abstract

The 18 ureidoceramide derivatives had been investigated for their cytotoxic activity against HT-29 colon cancer, Caki-2 renal cancer, A549 lung cancer, PC-3 prostate cancer, HL -60 leukemia cell using MTT assay. Cytotoxic activity was strongly influenced by the substituted alkyl chain length and the optimal alkyl chain length for cytotoxicity was C9-C12. (omitted)

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