Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.237.1-237.1
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- 2003
Asymmetric synthesis of (2S, 3R, 4E) 5-Aryl-4-pentene-1,3-diol-2-aminoueras
Abstract
(2S 3R. 4E) 5-Aryl-4-pentene-1,3-diol-2-aminoueras had been synthesized for their cytotoxic activity. Pinene was oxidized with KMnO4 to give 2-hydroxy-3-pinanone. which treated with ethyl glycinate to yield iminoglycinate and then reacted with aldehyde derivatives and titanium enolate to afford 3-hydroxy aldol compounds. (omitted)
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