Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Reagentselective and positionselective epoxidation of 25(R)-1,4,6-spirostatrien-3-one and 25(R)-4,6-spirostadien-3$\beta$-ol

  • Ma, Eun-Sook (Department of Pharmacy, Catholic University of Daegu) ;
  • Kim, Hak-Soon (Department of Pharmacy, Catholic University of Daeg) ;
  • Kim, Eun-Jung (Department of Pharmacy, Catholic University of Daeg) ;
  • Jung, Won-Young (Department of Pharmacy, Catholic University of Daegu)
  • Published : 2003.04.01
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Abstract

Diosgenin(25(R)-spirost-5-en-3${\beta}$-ol) is the steroid saponin, was isolated from Mexican yam(Oioscorea). Estrogenic, progesterogenic and anti-inflammatory effects of diosgenin has been hypothesized due to its structural similarity to estrogen, progesterone precursors. And diosgenin had been reported to lower serum cholesterol in chicken and rabbits fed cholesterol and to decrease liver cholesterol in cholesterol-fed rats. (omitted)

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