Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.217.3-218
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- 2003
Purification and Partial Characterization of a Lectin with Potent Immunomodulatory Activity from the Mushroom Fomitella fraxinea
- Lee, Ji-Seon (College of Pharmacy, Chungnam National University, College of Pharmacy, Yeung-Nam University) ;
- Chung, Kyeong-Soo (College of Pharmacy, Chungnam National University) ;
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Sok, Dai-Eun
(College of Pharmacy, Chungnam National University)
- Published : 2003.04.01
Abstract
A novel lectin has been purified from the fruiting bodies of the mushroom, Fomitella fraxinea, which belongs to bracket fungi by a combination of ion-exchange chromatography on DEAE-cellulose and gel filtration chromatography on Sephacryl S-200 HR. The lectin, designated as FFrL, was a homotetrametric protein with a molecular weight of 50 kDa as demonstrated by SDS-PAGE (sodium dodecyl sulfate-polyacrylamide gel electrophoresis) and MALDI-TOF-MS(matrix assisted UV laser desorption/ionization time-of flight mass spectrometry). (omitted)
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