Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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The protective role of the polysaccharide Ginsan against Staphylococcus aureus : induction of NO and reduction of poinflammatory cytokines

  • Ahn, Ji-Yeon (Lab. of Immunology, Korea Institute of Radiological ＆ Medical Sciences (KIRAMS)) ;
  • Choi, In-Soo (Lab. of Immunology, Korea Institute of Radiological ＆ Medical Sciences (KIRAMS) ;
  • Song, Jie-Young (Lab. of Immunology, Korea Institute of Radiological ＆ Medical Sciences (KIRAMS) ;
  • Shim, Ji-Young (Lab. of Immunology, Korea Institute of Radiological ＆ Medical Sciences (KIRAMS) ;
  • Jung, In-Seong (Lab. of Immunology, Korea Institute of Radiological ＆ Medical Sciences (KIRAMS) ;
  • Yun, Yeon-Sook (Lab. of Immunology, Korea Institute of Radiological ＆ Medical Sciences (KIRAMS))
  • Published : 2003.04.01
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Abstract

Ginsan. a new polysaccharide isolated from Panax ginseng, has been previously reported as a good immunomodulator. In this study, we investigated the protective effect of Ginsan against a lethal sepsis induced by Staphylococcus aureus infection. The survival rate of mice treated with Ginsan 24 h prior to S. aureus infection was 80％ whereas PBS-treated mice showed 20％ of survival in the same infection. (omitted)

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