Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.190.2-191
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- 2003
Sodium Chloride Regulation of COX-2 gene expression is independent of aldosterone activated mineralocorticoid receptor
- Lim, Won-Chung (Department of Bioscience and Biotechnology, Sejong University) ;
- Park, Wan-Kyu (Department of Bioscience and Biotechnology, Sejong University) ;
- Lee, Young-Joo (Department of Bioscience and Biotechnology, Sejong University)
- Published : 2003.04.01
Abstract
Production of prostaglandins involved in renal salt and water homeostasis is modulated by regulated expression of the inducible form of cyclooxygenase-2 (COX-2) at restricted sites in the rat kidney. COX-2 expression in the kidney is regulated by dietary salt intake, but the mechanism of its action is not fully understood. We have previously that high salt regulates COX-2 expression in rat kidney. (omitted)
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