Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.188.2-189
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- 2003
Cytochrome P450 발현 및 기능 조절제의 탐색 및 응용에 관한 연구
- Kim, Nam-Hee (College of Pharmacy, Yeungnam University) ;
- Jeon, Tae-Won (College of Pharmacy, Yeungnam University) ;
- Hyun, Sun-Hee (College of Pharmacy, Yeungnam University) ;
- Kim, Chun-Hwa (College of Pharmacy, Yeungnam University) ;
- Lee, Sang-Kyu (College of Pharmacy, Yeungnam University) ;
- Lee, Dong-Wook (College of Pharmacy, Yeungnam University) ;
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Jeong, Tae-Cheon
(College of Pharmacy, Yeungnam University)
- Published : 2003.04.01
Abstract
To develop cytochrome P450 (P450) modulators with low toxicity from natural products, we have evaluated more than 20 compounds in mouse and rat models. Among those, the effects of 1,8-cineole and diallyl sulfide (DAS) were most profound in modulating P450 expression. In this presentation, the effects of 1,8-cineole and diallyl sulfide (DAS) on P450 expression were introduced. (omitted)
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