Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.176.1-176.1
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- 2003
Inhibition of hepatic stellate cell collagen synthesis by an aqueous extract isolated from Platycodon grandiflorum
- Lee, Kyung-Jin (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University) ;
- Jeong, Hye-Gwang (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University)
- Published : 2003.04.01
Abstract
The protective effects on hepatic fibrosis of an aqueous extract from the roots of Platycodon grandiflorum A. DC (Campanulaceae), Changkil (CK), in hepatic stellate cell line, CFSC-2G. The increased deposition of extracellular matrix by hepatic stellate cells following liver injury in a process known as activation is considered a key mechanism for increased collagen content of liver during the development of liver fibrosis. (omitted)
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