Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
- /
- Pages.171.2-171.2
- /
- 2003
Chemopreventive Effect of Retinoids on Cellular NF-kappaB Activity Induced by Alkylating Carcinogens in Human Epidermal Keratinocytes
- Cho, Eun-Jeong (Department of Clinical Pathology, and Bioindustry&Technology Research Institute, Kwangju Health College) ;
- Lee, Min-Hee (Department of Clinical Pathology, and Bioindustry&Technology Research Institute, Kwangju Health Colleg) ;
- Kim, Seung-Kyoon (Department of Clinical Pathology, and Bioindustry&Technology Research Institute, Kwangju Health Colleg) ;
- Lee, Young-Jong (Department of Clinical Pathology, and Bioindustry&Technology Research Institute, Kwangju Health Colleg) ;
- Moon, Ki-Young (Department of Clinical Pathology, and Bioindustry&Technology Research Institute, Kwangju Health College)
- Published : 2003.04.01
Abstract
Retinoids have been shown to be effective in suppressing tumor development in chemical carcinogens such as N-nitroso-N-methylurea (NMU) and N-nitroso-N-ethylurea (NEU) induced mammary tumors in various animals. However, retinoids-mediated chemopreventive process, linked to transcription factor NF-kappaB activation on chemoprevention has yet to be studied. (omitted)
Keywords