Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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13(E)-Labd-13-ene-8$\alpha$, 15-diol isolated from Brachyglottis monroi Induces Apoptosis on Human Breast Cancer MDA-MB231 cell line

  • Lim, Jin-A (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Lee, Jeong-Ho (Department of Third Medicine, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Lee, In-A (Department of Third Medicine, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Nigel, B (Plant Extracts Research Unit, New Zealand Institute for Crop ＆ Food Research Ltd) ;
  • Baek, Seung-Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University)
  • Published : 2003.04.01
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Abstract

The inhibitory effect of 13(E)-Labd-13-ene-8$\alpha$ 15-diol(1), isolated from the ethanol extract of Brachyglottis monroi, on the proliferation of human breast cancer MDA-MB231 cells was examined. Compound (1) at concentration as high as 16$\mu$/$m\ell$ has inhibited the proliferation of MDA-MB231 and this cytotoxic effect was increased in a time and dose-dependent manners. (omitted)

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