Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Antioxidant Effects of Hirsutanone Derivatives from Alnus Japonica on Copper Mediated human LDL Oxidation

  • Kim, Ju-Ryoung (Korea Research institute of Bioscience and Biotechnology) ;
  • Lee, Dae-Woo (Korea Research institute of Bioscience and Biotechnolog) ;
  • Lee, Woo-Song (Korea Research institute of Bioscience and Biotechnolog) ;
  • Cho, Kyung-Hyun (Korea Research institute of Bioscience and Biotechnolog) ;
  • Sok, Dai-Eun (College of Pharmacy, Chungnam National University) ;
  • Jeong, Tae-Sook (Korea Research institute of Bioscience and Biotechnology)
  • Published : 2003.04.01
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Abstract

Subendothelial accumulation of foam cells plays a key role in the initiation of atherosclerosis. These foam cells accumulate in fatty streaks that evolve to more complex fibrofatty or atheromatous plaques. Oxidized LDL may also be involved in atherogenesis by inducing smooth muscle cell proliferation and smooth muscle foam cell generation. (omitted)

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