Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.136.2-137
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- 2003
Inhibitory Effect of Rat Aortic Vascular Smooth Muscle Cell Proliferation by Luteolin
- Kim, Jin-Ho (College of Pharmacy, Chungbuk National University) ;
- Kim, Soo-Yeon (School of Agricultural Biotechnology, Seoul National University) ;
- Lim, Yong (School of Agricultural Biotechnology, Seoul National University) ;
- Park, Byeoung-Soo (School of Agricultural Biotechnology, Seoul National University) ;
- Pyo, Hyeong-Bae (School of Agricultural Biotechnology, Seoul National University) ;
- Yoo, Hwan-Soo (School of Agricultural Biotechnology, Seoul National University) ;
- Yun, Yeo-Pyo (School of Agricultural Biotechnology, Seoul National University)
- Published : 2003.04.01
Abstract
It was previously reported that luteolin, a flavone compound, displayed the potent anti-oxidant and anti-inflammatory effects, which have also been successful in reducing vascular smooth muscle cells(VSMCs) proliferation after arterial injury. Proliferation of VSMCs plays an important role in development of astherosclerosis. In this study, a possible anti-proliferative effect and its mechanism on rat aortic VSMCs by luteolin was investigated. (omitted)
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