Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Regulatory Effect of Atopic Allergic Reaction by Sargassum hemiphylum

  • Na, Ho-Jeong (Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University) ;
  • Moon, Phil-Dong (Department of Anatomy, College of Midicine, Wonkwang University) ;
  • Hong, Seung-Heon (Division of Ocean Science, Korea Maritime University) ;
  • Seo, Young-Wan (Department of Pharmacology, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Hyung-Min (Department of Pharmacology, College of Oriental Medicine, Kyung Hee University)
  • Published : 2003.04.01
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Abstract

We studied the effect of methanol extract of Sargassum hemiphylum(SH) on atopic allergic reaction. SH dose-dependently inhibited interleukin (IL)-8 and tumor necrosis factor (TNF)-$\alpha$ secretion from the PMA- plus A23187- stimulated HMC-1. SH also dose-dependently inhibited the histamine and $\beta$-hexosaminidase release from mast cells. (omitted)

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