Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.10b
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- Pages.178-178
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- 2003
Neoplastic Transformation of Immortalized Human Keratinocytes by 2,3,7,8-Tetrachlorodibenzo-P-Dioxin
- Kang, Mi-Kyung (Department of Toxicology, National Institute of Toxicological Research, KFDA) ;
- Kang, Ho-Il (Department of Toxicology, National Institute of Toxicological Research, KFDA) ;
- Park, Young-Sill (Department of Toxicology, National Institute of Toxicological Research, KFD) ;
- Ryeom, Tai-Kyung (Department of Toxicology, National Institute of Toxicological Research, KFDA) ;
- Eom, Mi-Ok (Department of Toxicology, National Institute of Toxicological Research, KFDA) ;
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Park, Mi-Sun
(Department of Toxicology, National Institute of Toxicological Research, KFDA)
;
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Jee, Seung-Wan
(Department of Toxicology, National Institute of Toxicological Research, KFDA)
;
- Kim, Ok-Hee (Department of Toxicology, National Institute of Toxicological Research, KFDA)
- Published : 2003.10.01
Abstract
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a prototype of many halogenated aromatic hydrocarbons, is a ubiquitous, persistent environmental contaminant and the most powerful carcinogen categorized by IARC. It is display high toxicity in animals and is associated with several cancers in human. Although the mechanism of carcinogenesis by TCDD is unclear, it is considered to be a non-genotoxic and rumor promoter.(omitted)