Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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Transforming Growth Factor-$\beta$ (TGF-$\beta$) Induces Invasion and Migration of MCF10A Human Breast Epithelial Cells

  • Kim, Eun-Sook (College of Pharmacy, Duksung Women′s University) ;
  • Kim, Mi-Sung (College of Pharmacy, Duksung Women′s University) ;
  • Aree Moon (College of Pharmacy, Duksung Women′s University)
  • Published : 2003.10.01
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Abstract

Transforming growth factor (TGF)-${\beta}$, a hormonally active polypeptide found in normal and transformed tissue, is a potent regulator of cell growth and differentiation. In this study, we examined the effect of TGF-${\beta}$ on invasion and motility of MCF10A human breast epithelial cells. TGF-${\beta}$ induced migration and invasive phenotype of the parental MCF10A cells in a dose-dependent manner.(omitted)

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