A Toxicogenomic Study to Assess Neurotoxic Mechanism of Methylmercury

  • Kim, Youn-Jung (Toxicology Laboratory, Korea Institute of Science & Technology) ;
  • Yun, Hye-Jung (Toxicology Laboratory, Korea Institute of Science & Technology) ;
  • Jeon, Hee-Kyung (Toxicology Laboratory, Korea Institute of Science & Technology) ;
  • Chai, Young-Gyu (Department of biochemistry, University of Hanyang) ;
  • Ryu, Jae-Chun (Toxicology Laboratory, Korea Institute of Science & Technology)
  • Published : 2003.10.01

Abstract

Methylmercury (MeHg) is a well-known neurotoxicant that causes severe damage to the central nervous system in humans. Many reports have shown that MeHg is poisonous to human body through contaminated foods and has released into the environment. Despite many studies on the pathogenesis of MeHg-induced central neuropathy, no useful mechanism of toxicity has been established so far.(omitted)

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