Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.10b
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- Pages.129-129
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- 2003
Transcriptional Profile and Cellular Effects on Treatment of Methylmercury Using Human Cdna Microarray
- Kim, Youn-Jung (Toxicology Laboratory, Korea Institute of Science & Technology) ;
- Yun, Hye-Jung (Toxicology Laboratory, Korea Institute of Science & Technology) ;
- Jeon, Hee-Kyung (Toxicology Laboratory, Korea Institute of Science & Technology) ;
- Chai, Young-Gyu (Department of biochemistry, University of Hanyang) ;
- Ryu, Jae-Chun (Toxicology Laboratory, Korea Institute of Science & Technology)
- Published : 2003.10.01
Abstract
Methylmercury is known to have devastating effects on the mammalian nervous system. When human neuroblastoma SH-SY5Y cells were treated with MeHg at sublethal concentrations (6.25 uM), up-regulated genes (39) & Down-regulated genes (19) were identified by microarray.(omitted)