Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.05a
- /
- Pages.80-80
- /
- 2003
Evaluation of skin sensitzation to skin whitening agents by local lymph node assay in Balb/c mice
- Lee, Jong-Kwon (Immunotoxicology Division, National Institute of Toxicological Research, KFDA) ;
- Park, Seung-Hee (Immunotoxicology Division, National Institute of Toxicological Research, KFD) ;
-
Park, Jae-Hyun
(Immunotoxicology Division, National Institute of Toxicological Research, KFD)
;
- Kim, Hyung-Soo (Immunotoxicology Division, National Institute of Toxicological Research, KFD) ;
- Chung, Seung-Tae (Immunotoxicology Division, National Institute of Toxicological Research, KFD) ;
- Juno H. Eom (Immunotoxicology Division, National Institute of Toxicological Research, KFD) ;
- Seo, Gi-Ho (Immunotoxicology Division, National Institute of Toxicological Research, KFD) ;
- Byun, Jung-A (Immunotoxicology Division, National Institute of Toxicological Research, KFD) ;
- Oh, Hye-Young (Immunotoxicology Division, National Institute of Toxicological Research, KFDA)
- Published : 2003.05.01
Abstract
The use of skin whitening agents have been recently increased in various kinds of cosmetic products, although there were reports that whitening agents might cause allergic contact dermatitis. A murine local lymph node assay (LLNA) has been developed as an alternative to guinea pigs for contact sensitization potential. This study was carried out to investigate the skin sensitization potential of three whitening agents, kojic acid, arbutin, azelaic acid, by LLNA using a non-radioistopic endpoint.(omitted)