대한치과보존학회:학술대회논문집 (Proceedings of the KACD Conference)
- 대한치과보존학회 2003년도 제120회 추계학술대회 제 5차 한ㆍ일 치과보존학회 공동학술대회
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- Pages.548-549
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- 2003
The effect of substance P on the secretion of interleukin-8 and MCP(Monocyte Chemoattractant Protein)-1 from human dental pulp cells
- Park, Sang-Hyuk (Department of Conservative Dentistry, College of Dentistry, Kyung-Hee University) ;
- Choi, Gi-Woon (Department of Conservative Dentistry, College of Dentistry, Kyung-Hee University) ;
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Park, Sang-Jin
(Department of Conservative Dentistry, College of Dentistry, Kyung-Hee University)
- 발행 : 2003.11.01
초록
Neurogenic inflammation has been recognized to play an important role in initiating and sustaining of pulp inflammation. The pulpal innervation may modulate several aspects of the inflammatory response via secretion of neuropeptides. In this present study, these neuropeptides that may be questioned about roles in recruiting leukocytes by inducing the release of the chemokine IL-8 in the pulp during inflammation were tested. The response of human pulp cells in releasing IL-8 after the stimulation with SP and/or CGRP were investigated.(omitted)
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