Surfactant-free microspheres of poly($\alpha$-caprolactone)/poly(ethylene glycol)/poly($\varepsilon$-caprolactone) triblock copolymers as a novel protein carriers

  • Published : 2002.10.01

Abstract

The aim of this study is to prepare biodegradable microspheres without use of any kind of surfactants or emulsifiers for a novel sustained delivery carriers of protein drugs. Poly(e-caprolactone)/poly(ethylene glycol)/poly(e-caprolactone) (CEC) triblock copolymer was synthesized by ring-opening of e-caprolactone with dihydroxy poly(ethylene glycol) and was used to make surfactant-free microspheres. (omitted)

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