Cytotoxic Constituents from Amanita pantherina(DC. ex Fr.) Krombh

  • Hong, Soon-Yong (Pharmacognosy Laboratory, College of Pharmacy, SungKyunKwan University) ;
  • Moon, Hyung-In (Laboratory of Immunomodulator, Korea Research Institute of Bioscience and Biotechnolog) ;
  • Zee, Ok-Pyo (Pharmacognosy Laboratory, College of Pharmacy, SungKyunKwan University)
  • Published : 2002.10.01

Abstract

In search for plant-derived cytotoxic compounds, it was found that the MeOH extracts obtained from Amanita pantherina(DC. ex Fr.) Krombh exhibited significant cytotoxic activity against human tumor cell line. The classical fractionation on the basis of the inhibitory activity upon the growth human tumor cell line. in vitro, and repeated column chromatography afforded several cytotoxic compounds from Amanita pantherina (DC, ex Fr.) Krombh. (omitted)

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