대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
- /
- Pages.354.1-354.1
- /
- 2002
Straightforward synthesis of 4'${\alpha}$ -C-hydroxymethyl branched novel carbocyclic nucleosides
- Oh, Jung-Hyo (College of Pharmacy, Chosun University) ;
- Kim, Kwan-Woo (College of Pharmacy, Chosun University) ;
-
Hong, Joon-Hee
(College of Pharmacy, Chosun University)
- 발행 : 2002.10.01
초록
Carbocyclic nucleosides are unique class in which a methylene group replaces the oxygen in the furan, which result in metabolic stability to endogenous phosphorylase. The biologically active natural carbocyclic nucleosides such as aristeromycin and neplanocin were found to possess interesting biological properties including antiviral and antitumor activity. (omitted)
키워드