대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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- Pages.316.3-317
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- 2002
Induction of Differentiation in HI-60 Human leukemia cells by Acteoside.
- Lee, Kyung-Won (College of Pharmacy, Kyung Hee University) ;
- Choi, jung-Hye (College of Pharmacy, Kyung Hee University) ;
- Lee, kyung-Tae (College of Pharmacy, Kyung Hee University) ;
- Lee, yong-Sup (Division of Life Sciences, Korea Institute of Science and Technology) ;
- Kim, hyoung-Ja (Division of Life Sciences, Korea Institute of Science and Technology) ;
- Pak , Hee-Juhn (Division of Applid Science, Sanji University)
- 발행 : 2002.10.01
초록
In previous reports, we exhibited that acteoside showed significant cytotoxicity against various cancer cells. In this study we investigated that acteoside is capable of inducing differentiation in HL -60 human leukemia cell line. After being treated with acteoside, the growth curve was decreased remakably in a dose- and time-dependent manner, and cell doubling time was delayed. Exposure of cells to 20
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