Temperature Regulates Melanin Synthesis in Mel-Ab Cells

  • Kim, Dong-Seok (Department of Dermatology. Seoul National University College of Medicine) ;
  • Kim, Sook-Young (Department of Dermatology. Seoul National University College of Medicine) ;
  • Lee, Jai-Eun (Department of Dermatology. Seoul National University College of Medicine) ;
  • Park, Kyoung-Chan (Department of Dermatology. Seoul National University College of Medicine)
  • Published : 2002.10.01

Abstract

Temperature change is one of the major environmental factors to influence human skin. However. the relationship between temperature and melanogenesis has received little attention. In the present study. we investigated the effects of temperature change including heat shock on melanogenesis using a mouse melanocyte cell line, Mel-Ab. Our results demonstrated that cells maintained at 37$^{\circ}C$ showed maximal melanin synthesis. (omitted)

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