Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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The anti-inflammatory activity of Kalopanax pictus bark extract (V). Effects of saponins from KP on $NF-_K/B$ and elastase activities

  • Li, Da-Wei (Natural Product Research Institute, Seoul National University) ;
  • Ahn, Kwang-Seok (Natural Product Research Institute, Seoul National University) ;
  • Joo, Eun-Ji (Natural Product Research Institute, Seoul National University) ;
  • Cho, So-Yean (Korea Food ＆ Durg Administration) ;
  • Jeong, Choon-Sik (College of Pharmacy, Duksung Women′s University) ;
  • Lee, Eun-Bang (Natural Product Research Institute, Seoul National University) ;
  • Kim, Yeong-Shik (Natural Product Research Institute, Seoul National University)
  • Published : 2002.10.01
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Abstract

In the previous studies. we confirmed the anti-inflammatory components of Kalopanax pictus bark using activity-guided fractionation in vivo. For the elucidation of anti-inflammatory mechanism, we evaluated the effects of these components on the inhibition of NF-$\sub$K/B activity and human leukocyte elastase. A cell-based assay system developed in our laboratory was used in transfectant RAW 264.7 cells. (omitted)

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