Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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GREEN TEA EXTRACT INHIBITS CATECHOLAMINE RELEASE IN THE PERFUSED RAT ADRENAL GLAND

  • Lim, Dong-Yoom (Department of Pharmacology, College of Medicine, Chosun University) ;
  • Shin, Hye-Gyeong (Department of Pharmacology, College of Medicine, Chosun University)
  • Published : 2002.10.01
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Abstract

The present study was designed to investigate the effects of green tea extract (GTE) and epigallocatechin gallate (EGCG) on secretion of catecholamines (CA) in the isolated perfused rat adrenal gland. In the presence of GTE (100 ${\mu}$g/$m\ell$) into an adrenal vein for 60 min. CA secretory responses evoked by ACh (5.32 mM), high K＋ (56 mM) and Bay-K-8644 (10 ${\mu}$M for 4 min) from the isolated perfused rat adrenal glands were greatly inhibited in a time-dependent fashion. (omitted)

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