Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Inhibitory Effects of 1,3-Selenazol-4-one Derivatives on Mushroom Tyrosinase

  • Choi, Sang-Yoon (Graduate School of East-West Medical Science, Kyung Hee University) ;
  • Koketsu, Mamoru (Department of Chemistry, Faculty of Engineering, Gifu University) ;
  • Ishiharab, Hideharu (Department of Chemistry, Faculty of Engineering, Gifu University) ;
  • Kim, Ho-Cheol (Department of Chemistry, Faculty of Engineering, Gifu University) ;
  • Kim, Sun-Yeou (Department of Chemistry, Faculty of Engineering, Gifu University)
  • Published : 2002.10.01
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Abstract

This study reports depigmenting potency of 1,3-selenazol-4-one derivatives. which would be based upon the finding of direct inhibition to mushroom tyrosinase. 1,3-Selenazol-4-one derivatives exhibited inhibitory effect on dopa oxidase activity of mushroom tyrosinase. In this study. inhibitory effects of six kinds of 1,3-selenazol-4-one derivatives (3a, 3c, 3d, 3e, 3g and 3i) on mushroom tyrosinase were investigated. (omitted)

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