Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.241.1-241.1
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- 2002
Determination of bioavailability of tolperisone HCI by HPLC
- Yang, Sang-In (College of Pharmacy, Sungkyunkwan University) ;
- Choi, Sun-Hee (College of Pharmacy, Sungkyunkwan University) ;
- Lee, Seung-Jin (College of Pharmacy, Sungkyunkwan University) ;
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Jang, Choon-Gon
(College of Pharmacy, Sungkyunkwan University)
;
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Lee, Seok-Yong
(College of Pharmacy, Sungkyunkwan University)
- Published : 2002.10.01
Abstract
Tolperisone hydrochloride is used as a muscle relaxant. Very few assay methods of tolperisone were reported. such as potentiometry. spectrophotometry and high performance thin layer chromatography. In addition. there is no report related to HPLC method to determine the tolperisone level in biological sample. In this study, A very sensitive reverse phase high performance liquid chromatographic (RP-HPLC) method for the determination of tolperisone HCI in plasma has been developed. (omitted)
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