Proteomic Analysis of Osmotic Stress Response in Streptomyces coelicolor A3(2) Using 2-Dimentional Gel Electrophoresis and MALDI-TOF Mass Spectrometry

An alternative sigma factor as encoded by the $\sigma$$\^$B/ gene in Streptomyces coelicolor A3(2) was known to be involved in the differentiation and osmotic stress response. Protein expression profiles of wild-type and a $\sigma$$\^$B/ mutant strain of S coelicolor A3(2), which is impaired in defense against osmotic stress, were compared in the absence and presence of osmotic stress, using 2-dimentional gel electrophoresis.(omitted)