Acetylcholine-Induced Calcium Current and Oscillation in Mouse Eggs

  • Kang, Da-Won (Department of Physiology, Gyeongsang National University) ;
  • Han, Jae-Hee (Department of Physiology, Gyeongsang National University) ;
  • Hong, Seong-Geun (Department of Physiology, Gyeongsang National University)
  • Published : 2002.06.01

Abstract

Our previous study has suggested that muscarinic receptor present in the mouse oocytes, and Ca/sup 2+/ waves elicited by acetylcholine (ACh) are similar to those induced by sperm. A numerous study reported that ACh could cause early activation events in mouse oocytes overexpressing the Ml muscarinic receptor (Williams et al., 1992; Moore et al., 1993; Kim et al., 1998). However, the physiological role of ACh during mouse embryonic development is poorly understood. (omitted)

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