Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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INHIBITION OF HEPATIC FIBROGENESIS INDUCED BY NITROSODIMETHYLAMINE IN RATS PRETREATED WITH BETAINE

  • Jung, Young-S (College of Pharmacy, Seoul National University) ;
  • Seo, Jung-M (College of Pharmacy, Seoul National University) ;
  • Chae, Yu-R (College of Pharmacy, Seoul National University) ;
  • Kwak, Hye-E (College of Pharmacy, Seoul National University) ;
  • Kim, Sang-K (College of Pharmacy, Seoul National University) ;
  • Kim, Young-C (College of Pharmacy, Seoul National University)
  • Published : 2002.05.01
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Abstract

Effects of betaine intake on hepatic fibrogenesis were examined in adult male SD rats treated with nitrosodimethylamine (DMN; 10 ${\mu}\ell$/kg/day, ip) 3 days a week for 4 weeks. From two weeks prior to initiation of DMN treatment until sacrifice rats were provided with drinking water containing 1 % betaine.(omitted)

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