Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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NITRIC OXIDE PRODUCTION BY 18$\beta$-GLYCYRRHETINIC ACID VIA NUCLEAR FACTOR-$\textsc{k}$B ACTIVATION IN MACROPHAGES

  • Kim, Ji-Young (Department of Pharmacy and Research Center for Proteineous Materials) ;
  • You, Ho-Jin (School of Medicine, Chosun University) ;
  • Jeong, Hye-Gwang (Department of Pharmacy and Research Center for Proteineous Materials)
  • Published : 2002.05.01
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Abstract

Glycyrrhizin, a triterpenoid saponin fraction of licorice, is reported to have anti-viral and anti-tumor activities and is metabolized to 18$\beta$-glycyrrhetinic acid (GA) in the intestine by intestinal bacteria. However, the mechanism underlying its effects is poorly understood.(omitted)

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