Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2002.05a
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- Pages.83-83
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- 2002
RADIATION SENSITIVITY DEPENDS ON OGG1 ACTIVITY STATUS IN HUMAN LEUKEMIA CELL LINES
- Hyun, Jin-Won (Department of biochemistry, Cheju University) ;
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Chung, Myung-Hee
(Department of Pharmacology, Seoul National University)
- Published : 2002.05.01
Abstract
To assess the role of 8-oxoguanine glycosylase (OGG1) in the cell defense against radiation injury, the radiation-induced cytotoxicities were compared between the mutant type KG-1 featuring a loss of OGG1 activity due to a homozygous mutation of Arg 229 G1n, and the wild type U937.(omitted)