Levan acetate를 이용한 hydrocortisone의 방출 제어

  • 임승 (전남대학교 물질 생물화학공학과) ;
  • 이기영 (전남대학교 물질 생물화학공학과) ;
  • 김동운 (광양보건대 환경학과) ;
  • 최춘순 (전남대학교 물질 생물화학공학과)
  • Published : 2001.11.07

Abstract

The preparation, characterization and drug release behaviour of hydrocortisone(HC) loaded levan acetate microparticles were investigated. Hydrophobic levan acetate was prepared by chemical modification of hydrophilic levan and micro particles were made by dialysis method or solvent evaporation method. The morphology of levan acetate was observed by SEM and drug release profiles were investigated at pH 7.4 and pH 1.2. Newly synthesised levan acetate can be used for carrier of drugs.

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