Structural Studies of Porcine Myeloid Antibacterial Peptide, PMAP-23 in DPC micelles by NMR Spectroscopy

  • Published : 2001.06.01

Abstract

Leukocytes are important elements in the host defense against microbial infections. A variety of antimicrobial peptides named as the cathelicidin family have been identified from leukocytes. PMAP-23 derived from porcine myeloid cells is an antimicrobial peptide belong to the cathelicidin family. PMAP-23 was reported to have potent growth inhibition activity against bacterial and tumor cells with no hemolytic activity.(omitted)

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