Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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NON-RADIO ISOTOPIC ENDPOINT FOR LOCAL LYMPH NODE ASSAY USING IMMUNOHISTOCHEMISTRY

  • Lee, Jong-Kwon (Immunotoxicology Division, National Institute of Toxicology Research, Korea Food and Drug Administration) ;
  • Park, Jae-Hyun (Immunotoxicology Division, National Institute of Toxicology Research, Korea Food and Drug Administratio) ;
  • Kim, Hyung-Soo (Immunotoxicology Division, National Institute of Toxicology Research, Korea Food and Drug Administratio) ;
  • Jang, Eun-Jung (Immunotoxicology Division, National Institute of Toxicology Research, Korea Food and Drug Administratio) ;
  • Hwang, In-Chang (Immunotoxicology Division, National Institute of Toxicology Research, Korea Food and Drug Administratio) ;
  • Jung, Seung-Tae (Immunotoxicology Division, National Institute of Toxicology Research, Korea Food and Drug Administratio) ;
  • Jun H. Eum (Immunotoxicology Division, National Institute of Toxicology Research, Korea Food and Drug Administratio) ;
  • Oh, Hye-Young (Immunotoxicology Division, National Institute of Toxicology Research, Korea Food and Drug Administration)
  • Published : 2001.10.01
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Abstract

A murine local lymph node assay (LLNA) has been developed as an alternative to guinea pig models for contact sensitization potential. However, a disadvantage of the LLNA is the need for the use of radioactive material. In this study, we aimed to investigate the development of non-radio isotopic endpoint for LLNA using immunohistochemistry.(omitted)

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