Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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PREVENTIVE EFFECT OF MUSHROOM PHELLINUS LINTEUS ON THE INHIBITION OF GAP JUNCTIONAL INTERCELLULAR COMMUNICATION BY $H_2O_2$ IS INVOLVED IN THE UP-REGULATION OF ERK2 AND p38

  • Kang, Kyung-Sun (Department of Veterinary Public Health Collage of Veterinary Medicine, Brain Korea 21 agricultural biotechnology, Seoul National University) ;
  • Cho, Jong-Ho (Department of Veterinary Public Health Collage of Veterinary Medicine, Brain Korea 21 agricultural biotechnology, Seoul National University) ;
  • Cho, Sung-Dae (Department of Veterinary Public Health Collage of Veterinary Medicine, Brain Korea 21 agricultural biotechnology, Seoul National University) ;
  • Kim, Kyung-Bae (Department of Veterinary Public Health Collage of Veterinary Medicine, Brain Korea 21 agricultural biotechnology, Seoul National University) ;
  • Lee, Ji-Hae (Department of Veterinary Public Health Collage of Veterinary Medicine, Brain Korea 21 agricultural biotechnology, Seoul National University) ;
  • Ahn, Nam-Shik (Department of Veterinary Public Health Collage of Veterinary Medicine, Brain Korea 21 agricultural biotechnology, Seoul National University) ;
  • Jung, Ji-Won (Department of Veterinary Public Health Collage of Veterinary Medicine, Brain Korea 21 agricultural biotechnology, Seoul National University) ;
  • Yang, Se-Ran (Department of Veterinary Public Health Collage of Veterinary Medicine, Brain Korea 21 agricultural biotechnology, Seoul National University) ;
  • Park, Joon-Suk (Department of Veterinary Public Health Collage of Veterinary Medicine, Brain Korea 21 agricultural biotechnology, Seoul National University) ;
  • Yoon, Byung-Su (Department of Biology, Kyunggi University) ;
  • Kim, Sung-Hoon (Graduate School of East-west medical Science, Kyunghee University) ;
  • Lee, Yong-Soon (Department of Veterinary Public Health Collage of Veterinary Medicine, Brain Korea 21 agricultural biotechnology, Seoul National University)
  • Published : 2001.10.01
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Abstract

Gap junctional intercellular communication (GJIC) is a cellular event underlying the tumor promotion process and that treatment to prevent the down-regulation or to up-regulate GJIC is important in preventing tumor promotion. We evaluated the potential preventive effect of Mushroom Phellinus Linteus (PL) against the promoting action of hydrogen peroxide ($H_2O$$_2$) in WB-F344 rat liver epithelial cells.(omitted)

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