Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.10a
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- Pages.153-153
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- 2001
MECHANISM OF CAPSAICIN-INDUCED APOPTOTIC CELL DEATH IN STOMACH CANCER CELL
- Pyo, Jong-Oak (Department of Biology, University of Ulsan) ;
- Yang, Kyung-Min (Department of Biology, University of Ulsa) ;
- Rina Yu (Department of Food and Nutrition, University of Ulsa) ;
- Choe, Suck-Young (Department of Food and Nutrition, University of Ulsa) ;
- Kim, Byung-Sam (Department of Biology, University of Ulsan)
- Published : 2001.10.01
Abstract
Capsaicin, a major pungent ingredient in red hot pepper, has long been used in food additives and drugs. We have previously reported that capsaicin induces apoptosis in Korean stomach cancer cell line, SNU-1. In the present study, the mechanism of capsaicin-induced apoptotic cell death was investigated in SNU-1. Treatment of capsaicin to SNU-1 produced dose-dependent increase of apoptotic cell death and ［Ca2＋］
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