Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.10a
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- Pages.83-84
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- 2001
CHEMOPREVENTION AGAINST DIETARY MUTAGENS IN HUMANS BY INGESTION OF CRUCIFEROUS VEGETABLES
- Steinkellner, Hans (Institute of Cancer Research, University of Vienna) ;
- Gsur, Andrea (Institute of Cancer Research, University of Vienn) ;
- Kundi, Michael (Institute of Environmental Hygiene, University of Vienn) ;
- Knasmuller, Siegfried (Institute of Cancer Research, University of Vienna)
- Published : 2001.10.01
Abstract
Results from laboratory experiments indicate that induction of phase II enzymes by dietary constituents leads to inactivation of genotoxins. In animal studies glutathione S-transferase (GST) induction was paralleled by a reduction of chemically induced tumours. However data on induction of phase II enzymes in humans is scarce. Therefore we carried out intervention studies in which we investigated the effect of cruciferous vegetables on GST induction, and studied the effects of these vegetables on meat derived urinary mutagenicity.(omitted)
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